Rapid Synthesis of Bradykinin in Solution

Rapid Synthesis of Bradykinin in Solution

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Two variants of the two-phase-purification method are examined, using the preparation of bradykinin as a MARSHMALLOWS SMALL model.In one synthesis, intermediate purification by liquid-liquid extraction was carried out after each completed elongation, in the other, new variant, the extractions were Seasonal Art performed after the deprotection steps.If not hampered by technical difficulties the second variant is more efficient.